Modulators of crescentic glomerulonephritis.

T cells in crescentic glomerulonephritis.

Crescent formation in glomerulonephritis (GN) is a manifestation of severe glomerular injury that usually results in a poor clinical outcome. In humans, crescentic GN is frequently associated with evidence of either systemic or organ-specific autoimmunity. T cells play a major role in initiation of adaptive immune responses that lead to crescentic injury. In experimental models of crescentic GN...

Crescentic glomerulonephritis and centrocytic lymphoma.

New insight on crescentic glomerulonephritis

4þ haematuria, but urinary sediments showed few red blood cells (1-2-1/high-power fields). His renal function recovered concomitantly with improvement of haemolytic anaemia; thus, haemolysis might also have contributed to the development of his renal dysfunction. Indeed, haemolysisrelated renal dysfunction has occurred in patients with HCV infection [1]. Our patient showed cryoglobulinaemia, bu...

Etiology and outcome of crescentic glomerulonephritis.

OBJECTIVE To determine the etiology, course and predictors of outcome in children with crescentic glomerulonephritis (GN). STUDY DESIGN Retrospective, descriptive study. SETTING Pediatric Nephrology Clinic at a referral center in Northern India. METHODS Clinic records of patients aged <18 year with crescentic GN diagnosed from 2001 - 2010 and followed at least 12 months were reviewed. Cre...

Scleroderma with crescentic glomerulonephritis: a case report

INTRODUCTION Systemic sclerosis or scleroderma is an autoimmune rheumatic disease characterized by organ-based fibrosis. Renal involvement in scleroderma occurs mainly in the form of scleroderma renal crisis, affecting 5 to 10% of patients. It remains one of the most important and immediately life-threatening complications of scleroderma, but the prognosis improves considerably after treatment ...